Metaplastic Breast Cancer

Metaplastic breast cancer (MBC) Treatment in Dubai at Emirates Hospitals Group. Metaplastic breast cancer (MBC) is a rare and aggressive form of breast cancer characterized by the presence of atypical cells that deviate from the usual ductal or lobular patterns of breast tissue. Making up about 1-5% of all breast cancers, MBC poses unique challenges in terms of diagnosis and treatment. At Emirates Hospitals Group, we are committed to providing patients with comprehensive care, utilizing advanced diagnostic techniques and cutting-edge treatment options. Our team of highly skilled breast surgeons, recognized as the best in Dubai, ensures that each patient receives personalized care tailored to their specific needs.

About Metaplastic Breast Cancer

Metaplastic breast cancer is distinguished by the presence of differentiated cells, often displaying a mix of different types of cancerous cells, such as squamous cells, spindle cells, and other forms. This cancer type typically presents as a palpable mass in the breast and may not show the same characteristics on imaging studies as more common types of breast cancer. MBC is more commonly diagnosed in younger women and can sometimes be mistaken for benign breast conditions.

Due to its aggressive nature, MBC often has a poorer prognosis compared to more common breast cancers. Understanding the characteristics and behaviors of this cancer is crucial for effective management and treatment.

Causes & Symptoms

At Emirates Hospitals Group, we are committed to providing patients with comprehensive care, utilizing advanced diagnostic techniques and cutting-edge treatment options.

Causes

The precise causes of metaplastic breast cancer remain unclear. However, several factors may contribute to its development:

1. Genetic Mutations: Inherited mutations in genes like BRCA1 and BRCA2 can increase the risk of developing various breast cancers, including MBC.
2. Hormonal Influence: Estrogen exposure is known to play a role in the development of many breast cancers, and hormonal fluctuations may contribute to the risk.
3. Environmental Factors: Exposure to certain environmental toxins or carcinogens may increase breast cancer risk, although specific links to MBC remain under investigation.
4. Age and Gender: MBC is more commonly diagnosed in women, particularly those under 50 years of age.

Symptoms

Symptoms of metaplastic breast cancer may include:

• Palpable Mass: A noticeable lump in the breast, which may feel hard or irregular in shape.
• Breast Changes: Alterations in the size, shape, or texture of the breast, including skin changes such as redness, swelling, or dimpling.
• Nipple Discharge: Unexplained discharge from the nipple, which may be clear or bloody.
• Pain or Tenderness: Localized pain or discomfort in the breast area.

Due to the aggressive nature of MBC, early detection is crucial for improving treatment outcomes.

Diagnosis

Diagnosing metaplastic breast cancer involves a multi-step process, including:

1. Clinical Breast Examination: A thorough physical examination by an oncologist to assess any abnormalities in the breast tissue.
2. Imaging Studies: Mammograms and breast ultrasounds are typically the first steps in imaging, although MRI may be employed for a more detailed view.
3. Biopsy: A definitive diagnosis is made through a biopsy, wherein a sample of breast tissue is collected and examined microscopically for cancerous cells. The type of biopsy may vary, including fine-needle aspiration, core needle biopsy, or excisional biopsy.
4. Pathological Analysis: Pathologists analyze biopsy samples to confirm the presence of metaplastic cells and determine the cancer’s specific characteristics, including hormone receptor status and grade.

At Emirates Hospitals Group, we utilize advanced diagnostic techniques and technology to ensure accurate and timely diagnosis, allowing us to formulate effective treatment plans tailored to each patient.

Treatment

The treatment of metaplastic breast cancer is complex and may include various modalities, often determined by the cancer’s stage, grade, and individual patient factors. Treatment options may involve:

1. Surgery: Surgical intervention may involve lumpectomy or mastectomy, depending on the tumor’s size and location.
2. Chemotherapy: Given the aggressive nature of MBC, chemotherapy is often employed as a primary treatment option to eliminate cancer cells and reduce tumor size prior to surgery.
3. Radiation Therapy: Following surgery, radiation therapy may be recommended to reduce the risk of recurrence, especially in patients who have undergone breast-conserving surgery.
4. Targeted Therapy: In cases where specific markers are present, targeted therapies may be utilized to improve treatment effectiveness.
5. Hormone Therapy: If the cancer is hormone receptor-positive, hormone therapy may be incorporated into the treatment plan.