Wilson’s Disease

Wilson’s Disease is a rare genetic disorder in which the body is unable to properly metabolize and eliminate excess copper. This leads to copper accumulation in vital organs, particularly the liver, brain, and eyes, resulting in potentially serious health issues if left untreated. Early diagnosis and treatment are crucial to managing this condition and preventing long-term damage. At Emirates Hospitals Group, we offer specialized care for patients with Wilson’s Disease, utilizing advanced diagnostic tools and personalized treatment plans to manage the condition effectively.

Symptoms of Wilson’s Disease

The symptoms of Wilson’s Disease can vary depending on the affected organs and the stage of the disease. Common symptoms include:

• Liver symptoms: Fatigue, jaundice, swelling in the abdomen, or abnormal liver function tests.
• Neurological symptoms: Tremors, difficulty with speech or coordination, stiffness, and changes in behavior or mood.
• Psychiatric symptoms: Depression, anxiety, mood swings, and difficulty concentrating.
• Ocular symptoms: Kayser-Fleischer rings, which are copper deposits visible in the eyes.

If you experience any of these symptoms or have a family history of Wilson’s Disease, it is essential to seek medical evaluation to determine the appropriate diagnosis and treatment.

Diagnosis of Wilson’s Disease

At Emirates Hospitals Group, we use state-of-the-art technology to diagnose Wilson’s Disease. Our comprehensive diagnostic process includes:

• Blood and Urine Tests: Measuring copper levels in the blood and urine to assess copper accumulation in the body.
• Liver Biopsy: A small sample of liver tissue is taken to measure the amount of copper in the liver.
• Genetic Testing: Genetic testing may be recommended to identify mutations in the ATP7B gene, which is responsible for the disease.
• Eye Examination: An ophthalmologist may look for the presence of Kayser-Fleischer rings, which are often a hallmark of Wilson’s Disease.

Treatment Options for Wilson’s Disease

Wilson’s Disease is a chronic condition that requires long-term management. The goal of treatment is to reduce excess copper in the body and prevent further buildup. At Emirates Hospitals Group, we offer a multidisciplinary approach to Wilson’s Disease treatment, including:

• Chelation Therapy: Medications such as penicillamine or trientine are prescribed to bind copper and remove it from the body through urine. Chelation therapy is often the first line of treatment to quickly reduce copper levels in the body.
• Zinc Therapy: Zinc acetate may be used to block copper absorption in the intestines, preventing further buildup in the body. Zinc therapy is typically used for maintenance after chelation has reduced copper to safe levels.
• Dietary Modifications: Patients are advised to follow a low-copper diet by avoiding foods high in copper, such as liver, shellfish, nuts, and chocolate. Our nutritionists work closely with patients to create balanced meal plans that support their treatment.
• Liver Transplant: In advanced cases where the liver has suffered significant damage, a liver transplant may be necessary. Emirates Hospitals Group offers expert transplant services for patients with severe liver involvement.

Ongoing Monitoring and Follow-Up Care

Treatment for Wilson’s Disease requires lifelong management. Patients need regular monitoring of their copper levels, liver function, and overall health to ensure effective control of the condition. At Emirates Hospitals Group, we provide continuous follow-up care, including:

• Regular Blood and Urine Tests: To monitor copper levels and adjust medications as needed.
• Neurological and Psychiatric Support: Patients with neurological or psychiatric symptoms may require ongoing therapy or counseling to manage these aspects of the disease.
• Liver Health Assessments: Regular evaluations of liver function help prevent further damage and ensure timely interventions if complications arise.