Sickle Cell Disease Treatment in Dubai

Sickle Cell Disease Treatment in Dubai at Emirates Hospitals Group.We provide specialized care for patients with Sickle Cell Disease (SCD), a genetic blood disorder that affects the shape and function of red blood cells. Our expert hematologists are dedicated to diagnosing and managing Sickle Cell Disease using advanced medical techniques and personalized care plans. With a focus on both symptom relief and long-term health, we offer comprehensive support to help patients lead healthier lives. Whether you need a diagnosis, treatment, or ongoing care, Emirates Hospitals Group is here to guide you every step of the way.

About Sickle Cell Disease

Sickle Cell Disease (SCD) is an inherited blood disorder characterized by abnormal hemoglobin, known as hemoglobin S. This condition causes red blood cells, which are typically round and flexible, to become rigid and shaped like a crescent or sickle. These sickle-shaped cells can get stuck in blood vessels, blocking blood flow and leading to various complications.

Sickle Cell Disease is most common among individuals of African, Middle Eastern, and Mediterranean descent, but it can affect people from all ethnic backgrounds. The disorder is inherited in an autosomal recessive pattern, meaning a child must inherit one defective gene from each parent to develop the disease. If a person inherits only one sickle cell gene, they are considered carriers (sickle cell trait) but usually do not show symptoms.

Symptoms & Causes of Sickle Cell Disease

Symptoms of Sickle Cell Disease can vary, but they often include:

1. Pain Crises: One of the hallmark symptoms of SCD is periodic episodes of severe pain, known as vaso-occlusive crises. These occur when sickle-shaped cells block blood flow, causing pain in the chest, abdomen, joints, or bones.
2. Anemia: Due to the shortened lifespan of sickle cells (about 10-20 days compared to the normal 120 days), patients often experience chronic anemia, leading to fatigue, weakness, and pallor.
3. Swelling in Hands and Feet: Blocked blood flow can cause painful swelling in the extremities, a condition known as dactylitis.
4. Frequent Infections: The spleen, which helps fight infections, can become damaged over time due to the blockage of blood vessels, increasing the risk of infections.
5. Delayed Growth and Puberty: Children with Sickle Cell Disease may grow more slowly and reach puberty later than their peers due to chronic anemia and reduced oxygen delivery to tissues.
6. Vision Problems: Blocked blood vessels in the eyes can lead to retinal damage, potentially affecting vision.

Causes of Sickle Cell Disease:
Sickle Cell Disease is caused by a mutation in the HBB gene, which provides instructions for making hemoglobin. This mutation leads to the production of abnormal hemoglobin S, which causes red blood cells to distort into a sickle shape. The disease is inherited in an autosomal recessive manner, meaning both parents must carry the gene for a child to develop SCD.

Treatment for Sickle Cell Disease

Managing Sickle Cell Disease involves a combination of treatments aimed at alleviating symptoms, preventing complications, and improving quality of life. At Emirates Hospitals Group, our multidisciplinary approach includes:

1. Pain Management: Pain crises are one of the most challenging aspects of SCD. We offer a range of pain management options, including medications, intravenous fluids, and warm compresses to alleviate discomfort.
2. Blood Transfusions: Regular blood transfusions can help reduce the risk of stroke and other complications by increasing the number of healthy red blood cells in the bloodstream. However, transfusions may lead to iron overload, which is managed with chelation therapy.
3. Hydroxyurea Therapy: Hydroxyurea is a medication that helps increase the production of fetal hemoglobin, reducing the frequency and severity of pain episodes. It can also help decrease the need for blood transfusions.
4. Bone Marrow or Stem Cell Transplant: A bone marrow transplant is currently the only potential cure for SCD, but it carries significant risks and requires a compatible donor. This option is generally considered for patients with severe complications.
5. Gene Therapy: New advances in gene therapy offer promising potential for curing Sickle Cell Disease. This innovative approach involves modifying the patient’s own genes to correct the genetic defect causing the disorder.

Comprehensive Care & Monitoring: Regular check-ups and screenings are essential for monitoring complications of SCD, such as organ damage, stroke, or infections. Our team provides personalized care plans tailored to each patient’s needs.