Micropapillary Breast Cancer

Micropapillary breast cancer (MBC) Treatment in Dubai at Emirates Hospitals Group. Micropapillary breast cancer (MBC) is a rare and aggressive subtype of breast cancer characterized by its unique histological features. Recognized for its propensity to metastasize early and its distinct biological behavior, MBC poses significant challenges in both diagnosis and treatment. At Emirates Hospitals Group, we prioritize providing comprehensive, cutting-edge care to patients diagnosed with micropapillary breast cancer. Our dedicated team includes the best breast surgeon in Dubai, ensuring that patients receive individualized treatment plans based on the latest research and clinical practices.

About Micropapillary Breast Cancer

Micropapillary breast cancer is classified as a variant of invasive ductal carcinoma. It accounts for a small percentage of all breast cancer cases, but it is notable for its aggressive nature. Here are key characteristics:

• Histological Features: MBC is characterized by small clusters or “papules” of cancer cells surrounded by a fibrous stroma. This unique structure can be difficult to identify under a microscope, requiring specialized expertise.
• Biological Behavior: Micropapillary breast cancer tends to exhibit a higher likelihood of lymph node involvement and distant metastasis compared to other breast cancer types, contributing to its classification as a more aggressive form.
• Subtypes: MBC can be classified into two main types: pure micropapillary breast cancer, where the micropapillary pattern is the predominant feature, and mixed micropapillary breast cancer, where it coexists with other types of breast cancer.

Causes & Symptoms

At Emirates Hospitals Group, we prioritize providing comprehensive, cutting-edge care to patients diagnosed with micropapillary breast cancer.

The exact causes of micropapillary breast cancer are not well understood; however, several risk factors are associated with its development:

Risk Factors:

• Age: MBC is more commonly diagnosed in women over the age of 40.
• Hormonal Factors: Prolonged exposure to estrogen can increase the risk of breast cancer, including micropapillary subtypes.
• Family History: A family history of breast cancer or genetic mutations, such as BRCA1 and BRCA2, may contribute to an increased risk.

Symptoms of Micropapillary Breast Cancer:

• Lump or Mass: The most common symptom is a palpable lump or mass in the breast, which may be firm or hard.
• Changes in Breast Appearance: Patients may notice changes in breast size or shape, or skin dimpling or retraction.
• Nipple Discharge: Some individuals may experience discharge from the nipple, which can be clear, bloody, or serous.
• Pain: Although not always present, some women may report discomfort or pain in the breast area.

Diagnosis

Diagnosing micropapillary breast cancer involves a multi-faceted approach, including:

1. Clinical Breast Examination: A thorough examination by a healthcare professional to assess any abnormalities or lumps in the breast.
2. Imaging Studies:

1. • Mammography: This is the primary screening tool that helps identify suspicious masses.
   • Ultrasound: An ultrasound can further evaluate any abnormalities detected during mammography and provide information about the nature of the lump.
   • MRI: Magnetic resonance imaging may be used to obtain detailed images of the breast tissue and help assess the extent of the disease.

3. Biopsy: If a suspicious mass is detected, a biopsy is necessary to confirm the diagnosis. Types of biopsy may include:

1. • Fine Needle Aspiration (FNA): A thin needle is used to extract a small sample of cells.
   • Core Needle Biopsy: A larger needle is employed to obtain a more substantial tissue sample for pathological evaluation.
   • Surgical Biopsy: In certain cases, a surgical approach may be required to obtain tissue for diagnosis.

4. Pathological Evaluation: After a biopsy, the tissue sample is examined by a pathologist, who looks for the characteristic micropapillary patterns and confirms the diagnosis.

Treatment

The treatment plan for micropapillary breast cancer is highly individualized, taking into consideration the tumor stage, receptor status, and the patient’s overall health. Common treatment options include:

1. Surgery: Surgical intervention is typically the first line of treatment, which may involve:

1. • Lumpectomy: Removal of the tumor along with a margin of healthy tissue.
   • Mastectomy: Complete removal of one or both breasts, depending on the extent of the disease.

2. Radiation Therapy: Following surgery, radiation therapy may be recommended to eliminate any remaining cancer cells in the breast or surrounding tissue.
3. Chemotherapy: Due to the aggressive nature of micropapillary breast cancer, chemotherapy is often utilized, particularly if there is lymph node involvement or a high risk of recurrence.
4. Hormonal Therapy: If the cancer is hormone receptor-positive, hormonal therapy may be considered to help reduce the risk of recurrence.
5. Targeted Therapy: Targeted therapies may be employed depending on specific molecular characteristics of the tumor, especially if the cancer has certain genetic mutations.
6. Clinical Trials: Patients may have the option to participate in clinical trials exploring innovative treatment approaches and therapies.